Most people are familiar with the role digestive enzymes play in digestive health. They help to break down food into nutrients for absorption into the bloodstream. Systemic enzymes are different than digestive enzymes—they don’t just work in your digestive tract. Systemic enzymes can affect your entire body. Proteolytic (protein-digesting) enzymes can support fibrin breakdown in your circulatory system. Systemic enzymes benefit the entire body, supporting cardiovascular, joint and respiratory health.