Lack of adequate dietary calcium or an increase in bone resorption (breakdown) relative to formation, results in decalcification of bones. This can cause a loss of bone strength and thinning of bones, which is something of particular concern to women in their menopausal years. Clinical studies on post-menopausal women have shown that ipriflavone, a naturally occurring isoflavone, helps to maintain bone mineral density when combined with calcium. Bone Renew™ combines clinical amounts of ipriflavone with three highly absorbable forms of calcium to help support and maintain a healthy skeletal system, especially during the menopausal years when bone loss increases.