Bio-Aligned Chart Ultra Bone Balance™ Support for Bone Health Hormonal Regulation of Bone Mass Maintaining bone mass involves a balance between inhibition of bone resorption and stimulation of bone formation. Estrogen levels have a dramatic impact on bone mass by affecting this dynamic. The soy isoflavones genistein and daidzein, and the mineral boron support estrogenic activity. Ipriflavone, an isoflavone used extensively in Europe, has an inhibitory effect on osteoclastic cells that break down bone. Research has shown that supplementing ipriflavone together with calcium results in a reduction of bone loss in postmenopausal women.
Calcium Balance Declining estrogen levels in postmenopausal women have a negative impact on the important balance between calcium absorption and calcium loss. In addition, excess caffeine consumption and a high protein diet can lead to excretion of calcium in the urine. Some nutrients help prevent urinary losses of calcium.
Bone Synthesis: Organic Matrix Certain nutrients support synthesis of the specialized form of dense connective tissue--composed of collagen, non-collagen proteins and proteoglycans--that constitutes the organic matrix of bone.
Bone Synthesis: Mineral Building Blocks The bone loss that typically occurs during menopause can be offset by supplying the nutrients used as building blocks in the process of rebuilding bone tissue. Most bone mineral mass is composed of calcium. Other trace minerals are necessary for bone growth and calcium deposition in bones.
Calcium Absorption Estrogen improves calcium utilization in bones; therefore declining estrogen levels during menopause make optimal calcium absorption more difficult. Some forms of calcium are more easily absorbed and utilized in bone mineralization. In addition, certain nutrients enhance calcium absorption.
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